Is There Still a Role for Open Cordotomy in Cancer Pain Management?

Is there still a role for thiopurines in Crohn's disease?

Is there still a role for ultrasound in trauma?

Background The UK College of Emergency Medicine recommends that level 1 ultrasound competency is a basic standard for EM doctors and is now mandatory for career progression. Focused Assessment with Sonography in Trauma to include the detection of pleural fluid and pneumothorax (the Extended-FAST scan) forms part of this competency. We compare the diagnostic accuracy of E-FAST with the “gold sta...

Percutaneous cervical cordotomy in cancer pain.

The aim of this study was to review all published articles in the literature in English regarding percutaneous cervical cordotomy in cancer pain. Percutaneous cordotomy may be used to relieve unilateral pain below the level of the neck arising from a variety of causes. It is particularly indicated for unilateral chest pain associated with malignant disease. We searched for reports on MEDLINE an...

is there a role for genetic information in risk assessment and decision making in prostate cancer?

results a total number of 43 specimens were studied, from which 9 were obtained from patients with metastatic prostate cancer. the expression of five examined genes had no correlation with psa level and gleason score. the expression of amacr decreased in metastatic prostate cancer (p = 0.02). the expression of other genes showed no difference between metastatic and non-metastatic tumors (p > 0....

Is there still a role for neoadjuvant chemotherapy in head and neck cancer?

After approximately 20 years of conflicting results from chemotherapy in randomized trials in advanced head and neck cancer, three meta-analyses reviewed its use. All three concluded that chemotherapy was associated with a statistically significant advantage in survival, but that this was low (4% absolute benefit at 2 and 5 years). The improvement in survival was mainly based on the more robust...